반응형 SMALL 전체 글106 RNA interference (RNAi) RNA 간섭(영어: RNA interference;RNAi)은 세포 내에서 활성화 상태의 유전자와 그렇지 않은 유전자를 구별하는 역할을 한다. microRNA(miRNA)와 small interfering RNA(siRNA)와 같은 두 가지의 작은 RNA 분자(small RNA molecules)가 이 현상의 중심에 있다. RNA는 유전자의 직접적인 산물이며, 앞에서 언급된 작은 RNA(이하 small RNA로 표기)들은 다른 RNA에 결합하여 이들의 활성을 증가시키거나 감소시킬 수 있다. mRNA가 단백질을 발현하는 것을 억제하는 것이 적절한 예일 것이다. RNA 간섭 현상은 바이러스와 전위인자(transposon)와 같은 기생 유전자로부터 세포를 보호하는 기능을 가짐과 동시에 일반적인 유전자의 발현을.. 2021. 11. 12. Gene silencing Gene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene. Gene silencing can occur during either transcription or translation and is often used in research. In particular, methods used to silence genes are being increasingly used to produce therapeutics to combat cancer and other diseases, such as infectious diseases and neurodegenerative disorder.. 2021. 11. 12. micro RNA (miRNA) A microRNA (abbreviated miRNA) is a small single-stranded non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression. miRNAs function via base-pairing with complementary sequences within mRNA molecules. As a result, these mRNA molecules are silenced, by one or more of .. 2021. 11. 12. Conjugation Conjugation is the process by which one bacterium transfers genetic material to another through direct contact. During conjugation, one bacterium serves as the donor of the genetic material, and the other serves as the recipient. The donor bacterium carries a DNA sequence called the fertility factor, or F-factor. The F-factor allows the donor to produce a thin, tubelike structure called a pilus,.. 2021. 11. 11. 이전 1 ··· 22 23 24 25 26 27 다음 반응형 LIST